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  • Home
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Search Results for "diagnosis"

Alnylam is committed to providing the healthcare community with balanced, accurate, and high-quality information about our science, therapeutic areas, and products.

More than one search term is recommended to yield the most relevant results. By searching, you confirm that your query is unsolicited. 

For more information about our FDA-approved therapies, please see the Full Prescribing Information:

  • AMVUTTRA® (vutrisiran)
  • GIVLAARI® (givosiran)
  • ONPATTRO® (patisiran)
  • OXLUMO® (lumasiran)

Effectiveness and Utility of Genetic Testing in Establishing a Diagnosis of Hereditary Transthyretin Amyloidosis This link is a pdf

Neurofilament Light Chain in ATTR Amyloidosis with Cardiomyopathy: Analysis from the Phase 3 APOLLO-B Study This link is a pdf
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Real-World Persistency on Tafamidis: An Analysis of US Insurance Claims Data This link is a pdf
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Unmet Need in a Contemporary Cohort of Tafamidis-Treated Transthyretin Amyloid Cardiomyopathy Patients This link is a pdf
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Long-term Effects of Lumasiran on Kidney Stones and Nephrocalcinosis in Patients with Primary Hyperoxaluria Type 1 This link is a pdf
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Impact of Baseline Heart Failure Severity on Efficacy of Vutrisiran in Patients with Transthyretin Amyloidosis with Cardiomyopathy in the HELIOS-B Trial: A Subgroup Analysis This link is a pdf
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Insights from the phase 3 HELIOS-A study of vutrisiran in patients with hATTR-PN This link is a pdf
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This deck highlights data from the phase 3 HELIOS-A trial, including exploratory cardiac endpoints and post-hoc analyses.

Effect and Safety of Patisiran in Patients with Hereditary Transthyretin Amyloidosis with Polyneuropathy and Chronic Kidney Disease Results This link is a pdf
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Design and Rationale of cAPPricorn-1, a Phase 2 Study of Mivelsiran in Patients With Cerebral Amyloid Angiopathy This link is a pdf
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The journey to diagnosis of wild-type transthyretin-mediated (ATTRwt) amyloidosis: a path with multisystem involvement This link is a pdf

Diagnosis of hereditary transthyretin amyloidosis in patients with suspected chronic inflammatory demyelinating polyneuropathy unresponsive to intravenous immunoglobulins: results of a retrospective study This link is a pdf

Baseline Characteristics of Patients with ATTR Amyloidosis Enrolled into the ConTTRibute Registry This link is a pdf
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Musculoskeletal manifestations in patients with ATTR amyloidosis: Evidence from real-world analyses and clinical trials This link is a pdf
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Patisiran Global Open-Label Extension Study at 36 Months: Effect of Long-Term Treatment on Mortality and Ambulatory Function in Patients with hATTR Amyloidosis with Polyneuropathy This link is a pdf
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Patient Demographics and clinical characteristics at enrolment in ELEVATE, an international registry of Acute Hepatic Porphyria This link is a pdf
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Enrollment Characteristics and Real-World Insights Into Disease Burden and Givosiran Treatment in Patients With Acute Hepatic Porphyria in the ELEVATE Registry This link is a pdf
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Effect of Patisiran on Polyneuropathy and Cardiomyopathy in Patients with Hereditary Transthyretin Mediated (hATTR) Amyloidosis with a V122I or T60A Variant: A Phase 4 Observational Study This link is a pdf
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Clinical outcomes in patients with acute hepatic porphyria treated with givosiran who stopped hemin prophylaxis at study entry: Post hoc analyses from the phase 3 ENVISION study through month 36 This link is a pdf
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Long-term clinical outcomes of patients with acute hepatic porphyria who were not attack-free after 6-months of givosiran treatment: a subgroup analysis of the phase 3 ENVISION study This link is a pdf
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Clinical Outcomes in Patients with Acute Hepatic Porphyria Treated with Givosiran Who Stopped Hemin Prophylaxis at Study Entry: Post hoc Analyses from the Phase 3 ENVISION Study Through Month 36 This link is a pdf
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Diagnosis of ATTR This link is a pdf
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This deck highlights the red flag symptoms of ATTR and the tools to help achieve an accurate diagnosis.

Screening, Recognition, and Barriers to Diagnosis of ATTR This link is a pdf
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This deck highlights the screening, recognition, and barriers of diagnosis in ATTR.

Diagnosis of PH1 in CKD or Dialysis Patients This link is a pdf
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This handout informs the consequences of PH1 systemic manifestations due to declining kidney function and how to diagnose PH1.

Long-term clinical outcomes of patients with acute hepatic porphyria who were not attack-free after 6 months of givosiran treatment in a subgroup analysis of the phase 3 ENVISION study This link is a pdf
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Long-Term Efficacy and Safety in the Phase 3 ILLUMINATE-B Trial of Lumasiran for Primary Hyperoxaluria Type 1 in Infants and Young Children This link is a pdf
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Intended for US healthcare professionals. This site is intended to provide balanced, evidence-based information to support scientific exchange. It is not intended to provide medical advice or recommendations for clinical practice.

Information about investigational therapeutics or investigational uses of approved products does not establish the safety or efficacy of these therapeutics or uses, and there is no guarantee of FDA approval.

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