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© 2025 Alnylam Pharmaceuticals, Inc. All rights reserved.
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  • Home
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More than one search term is recommended to yield the most relevant results. By searching, you confirm that your query is unsolicited.

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Search Results for "manifestation"

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More than one search term is recommended to yield the most relevant results. By searching, you confirm that your query is unsolicited. 

For more information about our FDA-approved therapies, please see the Full Prescribing Information:

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Musculoskeletal Manifestations Associated with ATTR Amyloidosis This link is a pdf
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This slide deck provides disease education on ATTR amyloidosis, focusing on the musculoskeletal manifestations associated with the disease and their importance for early diagnosis and patient care.

ATTRv-PN Expert Opinion Slide Deck This link is a pdf
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Recommendations from a panel of experts for the diagnosis and treatment of hereditary transthyretin amyloidosis with polyneuropathy in the United States.

Symptoms and Disease Burden of ATTR This link is a pdf
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This slide deck provides an overview of the symptoms and disease burden of ATTR.

Hereditary ATTR Amyloidosis: A Closer Look at the V122I Variant External This link is a pdf
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V122I is the most common variant of hATTR amyloidosis in the United States and is most prevalent in patients of African American descent. Compared to other variants, patients with the V122I variant experience significant disease burden and poorer outcomes.

Musculoskeletal manifestations in patients with ATTR amyloidosis: Evidence from real-world analyses and clinical trials This link is a pdf
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Intended for US healthcare professionals. This site is intended to provide balanced, evidence-based information to support scientific exchange. It is not intended to provide medical advice or recommendations for clinical practice.

Information about investigational therapeutics or investigational uses of approved products does not establish the safety or efficacy of these therapeutics or uses, and there is no guarantee of FDA approval.

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