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This site is intended for US healthcare professionals.
© 2025 Alnylam Pharmaceuticals, Inc. All rights reserved.
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Search Results for "Alnylam"

Alnylam is committed to providing the healthcare community with balanced, accurate, and high-quality information about our science, therapeutic areas, and products.

More than one search term is recommended to yield the most relevant results. By searching, you confirm that your query is unsolicited. 

For more information about our FDA-approved therapies, please see the Full Prescribing Information:

  • AMVUTTRA® (vutrisiran)
  • GIVLAARI® (givosiran)
  • ONPATTRO® (patisiran)
  • OXLUMO® (lumasiran)

Patisiran: Premedications This link is a pdf
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Standard response letter on patisiran and premedications during the APOLLO, Global OLE, and APOLLO-B studies.

Lumasiran for Primary Hyperoxaluria Type 1: Analysis of Urinary Oxalate and eGFR Over Time in Patients With and Without Baseline Pyridoxine Use This link is a pdf
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Final Results from a Phase 1/2, 48-Month, Open-Label Extension Study of Givosiran in Patients with Acute Intermittent Porphyria This link is a pdf
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Long-term Efficacy and Safety of Lumasiran in Patients With Primary Hyperoxaluria Type 1: Final Analysis of the ILLUMINATE-A Trial This link is a pdf
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Outpatient Heart Failure Worsening in Patients with Cardiac Transthyretin Amyloidosis: Results from the APOLLO-B Trial This link is a pdf
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APOLLO Post-Hoc Analysis by Baseline Polyneuropathy Severity This link is a pdf
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A post-hoc analysis of the APOLLO trial was performed to evaluate the use of patisiran compared to placebo by baseline NIS quartile in patients with the the polyneuropathy of hATTR. This infographic summarizes the post-hoc analysis results, which were published in the journal Amyloid.

Long-term treatment with lumasiran: final results from the phase 2 open-label extension study This link is a pdf
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Efficacy and Safety of Givosiran in Patients with Acute Hepatic Porphyria: 36-Month Results of the Phase 3 ENVISION Randomized Clinical Trial This link is a pdf
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RNAi Therapy in ATTRv Amyloidosis with Polyneuropathy (HELIOS-A): Patient-reported Experiences and Preferences This link is a pdf
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Alnylam Act®: Effectiveness of Genetic Testing in Establishing a Diagnosis in Patients with Suspicion of Hereditary Transthyretin Amyloidosis This link is a pdf
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Intended for US healthcare professionals. This site is intended to provide balanced, evidence-based information to support scientific exchange. It is not intended to provide medical advice or recommendations for clinical practice.

Information about investigational therapeutics or investigational uses of approved products does not establish the safety or efficacy of these therapeutics or uses, and there is no guarantee of FDA approval.

Alnylam does not recommend or suggest use of its products in any manner inconsistent with the approved Prescribing Information.

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