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© 2025 Alnylam Pharmaceuticals, Inc. All rights reserved.
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Search Results for "Alnylam"

Alnylam is committed to providing the healthcare community with balanced, accurate, and high-quality information about our science, therapeutic areas, and products.

More than one search term is recommended to yield the most relevant results. By searching, you confirm that your query is unsolicited. 

For more information about our FDA-approved therapies, please see the Full Prescribing Information:

  • AMVUTTRA® (vutrisiran)
  • GIVLAARI® (givosiran)
  • ONPATTRO® (patisiran)
  • OXLUMO® (lumasiran)

Symptoms and Disease Burden of ATTR This link is a pdf
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This slide deck provides an overview of the symptoms and disease burden of ATTR.

Impact of Long-Term Blood Pressure Variability on Adverse Cardiovascular Outcomes in High- and Low-Risk Populations This link is a pdf
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Safety and Tolerability of ALN-AGT, an RNA Interference Therapeutic Targeting Hepatic Angiotensinogen Synthesis, in Hypertensive Patients during Sodium Depletion or Irbesartan Coadministration This link is a pdf
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Neurofilament Light Chain in ATTR Amyloidosis with Cardiomyopathy: Analysis from the Phase 3 APOLLO-B Study This link is a pdf
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ATTR Diagnostic and Staging Tools This link is a pdf
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This deck highlights diagnostic and staging tools for assessing patients with ATTR.

The Science of RNA interference (RNAi) This link is a pdf
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This slide deck provides an overview of the science of RNA interference (RNAi), including mechanism of action and delivery platforms.

Diagnosis of PH1 in CKD or Dialysis Patients This link is a pdf
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This handout informs the consequences of PH1 systemic manifestations due to declining kidney function and how to diagnose PH1.

Renin-Angiotensin System (RAS) In Hypertension Video This link is a pdf
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This video highlights how the up-regulation of RAS contributes to hypertension. This resource is intended to support scientific exchange. The information provided is not intended to serve as recommendations for clinical practice.

Consistent antihypertensive efficacy of the RNA interference therapeutic zilebesiran: Subgroup results from the KARDIA-1 phase 2 study in patients with hypertension This link is a pdf
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ATTR Disease Management This link is a pdf
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This deck highlights management and monitoring of patients with ATTR.

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This site is intended for US healthcare professionals.
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Intended for US healthcare professionals. This site is intended to provide balanced, evidence-based information to support scientific exchange. It is not intended to provide medical advice or recommendations for clinical practice.

Information about investigational therapeutics or investigational uses of approved products does not establish the safety or efficacy of these therapeutics or uses, and there is no guarantee of FDA approval.

Alnylam does not recommend or suggest use of its products in any manner inconsistent with the approved Prescribing Information.

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