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© 2026 Alnylam Pharmaceuticals, Inc. All rights reserved.
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Search Results for "diagnosis"

Alnylam is committed to providing the healthcare community with balanced, accurate, and high-quality information about our science, therapeutic areas, and products.

More than one search term is recommended to yield the most relevant results. By searching, you confirm that your query is unsolicited. 

For more information about our FDA-approved therapies, please see the Full Prescribing Information:

  • AMVUTTRA® (vutrisiran)
  • GIVLAARI® (givosiran)
  • ONPATTRO® (patisiran)
  • OXLUMO® (lumasiran)

Vutrisiran Treatment in Patients with Transthyretin Amyloidosis with Cardiomyopathy This link is a pdf
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This asset represents the HELIOS-B primary results, published in the New England Journal of Medicine, in slide deck form.

Dimension Analysis of EQ-5D in Patients with Acute Hepatic Porphyria Categorized by Annualized Attack Rate to Assess Any Relationship With Symptoms Occurring Between Attacks This link is a pdf
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Impact of Patisiran on Health Status and Quality of Life in Patients with Transthyretin Cardiac Amyloidosis This link is a pdf
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Real-World Treatment Patterns in Participants with Transthyretin Amyloidosis with Polyneuropathy Enrolled in the ConTTRibute Registry This link is a pdf
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Long-term Effects of Patisiran on Survival and Cardiac Parameters in Patients with Transthyretin-mediated Cardiac Amyloidosis: Post Hoc Analysis of APOLLO-B and Cardiac Subpopulation of APOLLO OLE This link is a pdf
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Primary Results from APOLLO-B Open-label Extension Study of Patisiran in Patients with Transthyretin Cardiac Amyloidosis This link is a pdf
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HELIOS-A: 18 Month Exploratory Cardiac Results from the Phase 3 Study of Vutrisiran in Patients with Hereditary Transthyretin Mediated Amyloidosis This link is a pdf
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Evaluation of Disease Progression in Patients with ATTR Amyloidosis with Cardiomyopathy Following Treatment with Patisiran: Post hoc Analysis of the APOLLO-B Study This link is a pdf
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Patisiran Treatment for ATTR Cardiac Amyloidosis: 18-Month Results of the Phase 3 APOLLO-B Study This link is a pdf
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Impact of givosiran treatment on symptoms between acute attacks of acute hepatic porphyria as assessed by dimension-level analysis of EQ-5D data from the ENVISION study This link is a pdf
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Dimension analysis of EQ-5D in patients with acute hepatic porphyria categorized by annualized attack rate to assess any relationship with symptoms occurring between attack This link is a pdf
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ATTR Management Guidelines This link is a pdf
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This deck highlights published guidelines on diagnosis, treatment and disease management of ATTR.

Diagnosing AHP Infographic This link is a pdf
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This infographic discusses the clinical and demographic presentation of an AHP patient and how to assess for AHP diagnosis.

Identifying AHP module This link is a pdf
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This educational module will illustrate patients with AHP, describe common AHP symptoms and summarize how patients present to the various specialties involved in managing these patients

Diagnosing PH1 Infographic This link is a pdf
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This infographic discusses the clinical and demographic presentation of a PH1 patient and how to assess for PH1 diagnosis

Potential Predictors of PH1 in Pediatric Patients This link is a pdf
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The handout details potential clinical characteristics that pediatric patients may present with which should warrant suspicion for PH1.

ATTR symptoms and manifestations early indicators This link is a pdf
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This deck highlights early indicators of ATTR and systemic manifestations.

Musculoskeletal Manifestations Associated with ATTR Amyloidosis This link is a pdf
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This slide deck provides disease education on ATTR amyloidosis, focusing on the musculoskeletal manifestations associated with the disease and their importance for early diagnosis and patient care.

Explore ATTR-CM This link is a pdf
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This slide deck presents of overview of ATTR amyloidosis, covering pathophysiology, disease manifestations and the clinical burden of ATTR-CM.

ATTR Screening and Carrier Management This link is a pdf
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This deck highlights tools for ATTR screening and recommendations for the management of hATTR carriers.

Hereditary ATTR Amyloidosis: A Closer Look at the V1221 Variant This link is a pdf
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V122I is the most common variant of hATTR amyloidosis in the United States and is most prevalent in patients of African American descent. Compared to other variants, patients with the V122I variant experience significant disease burden and poorer outcomes.

Diagnosing AHP This link is a pdf
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AHP Diagnosis

ASPIRE: Amyloidosis Industry Collaborative This link is a pdf
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ASPIRE: Amyloidosis Industry Collaborative convenes leading companies to address some of the most urgent issues faced by the amyloidosis community. Through partnership we are driven to shift the discourse and demonstrate what can be done when leaders work together on behalf of rare disease patients. ASPIRE aims to accelerate progress in the areas of diagnosis, care, and addressing health disparities through collaborative project design and shared resources, arriving at solutions that address common challenges and unmet need.

ATTR Disease Management This link is a pdf
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This deck highlights management and monitoring of patients with ATTR.

Understanding ATTR Amyloidosis This link is a pdf
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Understanding ATTR amlyloidosis: This slide deck highlights an overview of ATTR amyloidosis pathophysiology, symptom onset and prevalence

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Intended for US healthcare professionals. This site is intended to provide balanced, evidence-based information to support scientific exchange. It is not intended to provide medical advice or recommendations for clinical practice.

Information about investigational therapeutics or investigational uses of approved products does not establish the safety or efficacy of these therapeutics or uses, and there is no guarantee of FDA approval.

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