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Zilebesiran: KARDIA-3 Study
Standard response letter on zilebesiran and the KARDIA-3 study, an ongoing phase 2 study evaluating the efficacy and safety of zilebesiran in patients with high CV risk and hypertension that is not adequately controlled with at least 2 standard-of-care antihypertensives.
Standard response letter on zilebesiran and the KARDIA-3 study, an ongoing phase 2 study evaluating the efficacy and safety of zilebesiran in patients with high CV risk and hypertension that is not adequately controlled with at least 2 standard-of-care antihypertensives.
Zilebesiran: Phase 1 Study Overview
Standard response letter on the phase 1 study of zilebesiran, a study evaluating the safety, PK , PD, as well as exploratory antihypertensive efficacy of zilebesiran in patients with hypertension.
Standard response letter on the phase 1 study of zilebesiran, a study evaluating the safety, PK , PD, as well as exploratory antihypertensive efficacy of zilebesiran in patients with hypertension.
Zilebesiran: KARDIA-1 Study
Standard response letter on zilebesiran and the KARDIA-1 study, an ongoing phase 2 study evaluating the efficacy and safety of zilebesiran dosing regimens for adults with mild to moderate hypertension.
Standard response letter on zilebesiran and the KARDIA-1 study, an ongoing phase 2 study evaluating the efficacy and safety of zilebesiran dosing regimens for adults with mild to moderate hypertension.
Patisiran: Cardiac Results from the Global OLE Study
Standard response letter on patisiran and cardiac results in the Global OLE study, a study evaluating the long-term efficacy and safety of patisiran in patients with the polyneuropathy of hATTR.
Standard response letter on patisiran and cardiac results in the Global OLE study, a study evaluating the long-term efficacy and safety of patisiran in patients with the polyneuropathy of hATTR.
Insights from the phase 3 HELIOS-A study of Vutrisiran in patients with hATTR-PN.
This deck highlights data from the phase 3 HELIOS-A trial, including exploratory cardiac endpoints and post-hoc analyses.
This deck highlights data from the phase 3 HELIOS-A trial, including exploratory cardiac endpoints and post-hoc analyses.
Lumasiran: Use in Kidney Transplantation
Standard response letter on the use of lumasiran in patients who have had an isolated kidney transplant.
Standard response letter on the use of lumasiran in patients who have had an isolated kidney transplant.
Identifying AHP module
This educational module will illustrate patients with AHP, describe common AHP symptoms and summarize how patients present to the various specialties involved in managing these patients
This educational module will illustrate patients with AHP, describe common AHP symptoms and summarize how patients present to the various specialties involved in managing these patients
Insights from the HELIOS-A Study
This deck highlights data from the Phase 3 HELIOS-A trial of vutrisiran in patients with hATTR-PN.
This deck highlights data from the Phase 3 HELIOS-A trial of vutrisiran in patients with hATTR-PN.
Hereditary ATTR Amyloidosis: A Closer Look at the V1221 Variant
V122I is the most common variant of hATTR amyloidosis in the United States and is most prevalent in patients of African American descent. Compared to other variants, patients with the V122I variant experience significant disease burden and poorer outcomes.
V122I is the most common variant of hATTR amyloidosis in the United States and is most prevalent in patients of African American descent. Compared to other variants, patients with the V122I variant experience significant disease burden and poorer outcomes.
