Zilebesiran

Click below to learn more about zilebesiran through educational and scientific materials. 

MOA of zilebesiran depicting siRNA loading into RISC
MOA of zilebesiran depicting siRNA loading into RISC

About Zilebesiran

For more information about data regarding zilebesiran, please visit our Congresses & Publications page

 


 

Currently Enrolling Trials

Phase/Status

Trial Name

Description

Phase 3
ENROLLING

Image
ZENITH LOGO


 

ZENITH: A Phase 3 Global, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Zilebesiran in Addition to Standard of Care in Reducing Major Adverse Cardiovascular Events in Adult Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

  • Is 18 years or older for patients with established cardiovascular disease (CVD) may be eligible*

ClinicalTrials.gov: NCT07181109

For more information about ZENITH

  • Call study information center at 1-877-256-9526
  • Email Medical Information at medinfo@alnylam.com

Phase/Status

Phase 3
ENROLLING

Trial Name

Image
ZENITH LOGO


 

Description

ZENITH: A Phase 3 Global, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Zilebesiran in Addition to Standard of Care in Reducing Major Adverse Cardiovascular Events in Adult Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

  • Is 18 years or older for patients with established cardiovascular disease (CVD) may be eligible*

ClinicalTrials.gov: NCT07181109

For more information about ZENITH

  • Call study information center at 1-877-256-9526
  • Email Medical Information at medinfo@alnylam.com

*Additional eligibility criteria apply.